Medical Case Study: Abdominal pain, fatigue, and weight loss in a young woman
- manasvininori
- 2 days ago
- 1 min read

A 25-year-old woman presents to her primary care physician with abdominal pain, bloating, and frequent diarrhea that have persisted for the past three months. She reports experiencing symptoms several times a week, particularly after meals. The patient also complains of fatigue and has unintentionally lost eight pounds over the past two months.
She has no prior medical history and does not take medications. Her family history reveals that her mother has an autoimmune disease.
On physical exam, her temperature is 98.6°F. Her reports suggested she was not comfortable when her abdomen was examined. The patient appears slightly pale.
Lab Results:
Mild anemia
Elevated ESR and CRP (inflammatory markers)
Positive tissue transglutaminase (tTG-IgA) antibody test
Low iron levels
The possible conditions are:
1. Irritable Bowel Syndrome (IBS)
Irritable Bowel Syndrome (IBS) is a gastrointestinal disorder that affects the stomach and intestines. Symptoms include abdominal pain, bloating, gas, diarrhea, constipation, or a combination of these.
2. Ulcerative Colitis
Ulcerative colitis is a chronic inflammatory bowel disease that causes inflammation and ulcers in the lining of the colon and rectum. Common symptoms include abdominal pain, bloody diarrhea, fatigue, weight loss, and an urgent need to have bowel movements.
3. Celiac Disease
Celiac disease is an autoimmune disorder in which consuming gluten triggers an immune response that damages the small intestine. Symptoms may include diarrhea, bloating, abdominal pain, fatigue, weight loss, anemia, and nutrient deficiencies.
Sources:
Thank you for reading,
Manasvini Nori
Answer:
Celiac Disease: The woman's symptoms are abdominal pain, bloating, diarrhea, fatigue, weight loss, anemia, and a positive tTG-IgA antibody test. This condition requires a gluten-free diet and follow-up with a gastroenterologist.



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